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CAS号 | 16980-89-5 | 货号 | BCP09391 |
中文名 | 布拉地新 | ||
英文名 | Bucladesine sodium | ||
中文别名 | 二丁酰环磷腺苷钠;布拉地辛; | ||
英文别名 | Dibutyryl-cAMP, sodium salt; DBcAMP sodium salt; | ||
SMILES | CCCC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C4C(O3)COP(=O)(O4)[O-])OC(=O)CCC.[Na+] | ||
化学名称 | |||
分子式 | C18H23N5NaO8P | 分子量 | 491.37 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Bucladesine sodium salt is a cell-permeable analog of cAMP that activates cAMP-dependent protein kinases and is a phosphodiesterase inhibitor. Combined with other reagents, dibutyryl-cAMP promotes differentiation of neural stem/progenitor cells (NSPCs) and other cell lines and increases survival rates of NSPCs and differentiation into neurons in vivo. Promotes neurite outgrowth in cell cultures. Dibutyryl-cAMP has anti-inflammatory activity and is used to promote wound healing. Choline acetyltransferase and vesicular acetylcholine transporter mRNA are increased in cells treated with dibutyryl-cAMP. |
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