布拉地新
| CAS号 | 16980-89-5 | 货号 | BCP09391 |
| 中文名 | 布拉地新 | ||
| 英文名 | Bucladesine sodium | ||
| 中文别名 | 二丁酰环磷腺苷钠;布拉地辛; | ||
| 英文别名 | Dibutyryl-cAMP, sodium salt; DBcAMP sodium salt; | ||
| 分子式 | C18H23N5NaO8P | 分子量 | 491.37 |
| 生物活性 | Bucladesine sodium salt is a cell-permeable analog of cAMP that activates cAMP-dependent protein kinases and is a phosphodiesterase inhibitor. Combined with other reagents, dibutyryl-cAMP promotes differentiation of neural stem/progenitor cells (NSPCs) and other cell lines and increases survival rates of NSPCs and differentiation into neurons in vivo. Promotes neurite outgrowth in cell cultures. Dibutyryl-cAMP has anti-inflammatory activity and is used to promote wound healing. Choline acetyltransferase and vesicular acetylcholine transporter mRNA are increased in cells treated with dibutyryl-cAMP. | ||
| 信号通路 | GPCR/G Protein Wnt/Stem Cell | ||
| 靶 点 | PKA | ||
结构式
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