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CAS号 | 138908-40-4 | 货号 | BCP44544 |
中文名 | CL 316243 | ||
英文名 | CL 316243 | ||
中文别名 | |||
英文别名 | CL 316243; CL316243; CL-316,243; CL 316,243; CL316,243. HP 186; HP-186; HP186; | ||
SMILES | CC(CC1=CC2=C(C=C1)OC(O2)(C(=O)[O-])C(=O)[O-])NCC(C3=CC(=CC=C3)Cl)O.[Na+].[Na+] | ||
化学名称 | |||
分子式 | C20H18ClNO7.2Na | 分子量 | 465.79 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | CL-316243 is a potent and highly selective β3-adrenoceptor agonist (EC50 = 3 nM); > 10000-fold selective over β1 and β2 receptors. CL-316243 restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice. CL-316,243 enhances insulin-stimulated glucose disposal in nonobese rats. CL 316243 possesses anti-obesity and anti-diabetic effects and consequently may be useful for treating obesity as well as non-insulin-dependent diabetes mellitus in obese persons, without causing excessive side effects. |
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