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CAS号 | 1380782-27-3 | 货号 | BCP48541 |
中文名 | T2AA | ||
英文名 | T2AA | ||
中文别名 | |||
英文别名 | |||
SMILES | C1=CC(=CC=C1O)OC2=C(C=C(C=C2I)CC(CO)N)I | ||
化学名称 | |||
分子式 | C15H15I2NO3 | 分子量 | 511.09 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | T2AA is a proliferating cell nuclear antigen (PCNA) inhibitor. T2AA inhibits PCNA/PIP-box peptide interaction (IC50 ~1 μM), leading to the suppression of DNA replication stress by stalling DNA replication forks. T2AA inhibits the interaction of PCNA with DNA polymerase δ and arrests cell growth in S-phase. |
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