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CAS号 | 9014-02-2 | 货号 | BCP48970 |
中文名 | 新制癌菌素 | ||
英文名 | Zinostatin | ||
中文别名 | |||
英文别名 | Neocarzinostatin; Vinostatin; | ||
SMILES | CC1C(C(C(C(O1)OC2C3CC#CC4C(O4)(C#CC3=CC2OC(=O)C5=C(C=CC6=C5C=C(C=C6C)OC)O)C7COC(=O)O7)NC)O)O | ||
化学名称 | |||
分子式 | C35H35NO12 | 分子量 | 661.66 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Zinostatin is an enediyne antineoplastic antibiotic hybrid containing an aminoglycoside chromophore. Zinostatin is isolated from the bacterium Streptomyces carzinostaticus. The aminoglycoside component of zinostatin intercalates into DNA and the benzene diradical intermediate of the enediyne core binds to the minor groove of DNA, resulting in single- and double-strand breaks in DNA and apoptosis. |
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