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CAS号 | 1338247-30-5 | 货号 | BCP17224 |
中文名 | BMS-3 | ||
英文名 | BMS-3 | ||
中文别名 | |||
英文别名 | BMS 3; BMS3; | ||
SMILES | |||
化学名称 | |||
分子式 | C17H12Cl2F2N4OS | 分子量 | 429.27 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | BMS-3 is a LIM kinase 1 (LIMK1) inhibitor. LIMK inhibition with 1 μM BMS-3 damaged MTOC protein localisation to spindle poles, undermined the formation and positioning of functional MTOC and thus disrupted spindle formation and chromosome alignment. These effects were phenocopied by microinjection of LIMK1 antibody into mouse oocytes. LIM kinase 1 (LIMK1) activity is essential for cell migration and cell cycle progression. |
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