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CAS号 | 133052-90-1 | 货号 | BCP08311 |
中文名 | GF109203X | ||
英文名 | GF109203X | ||
中文别名 | |||
英文别名 | Bisindolylmaleimide I;GF 109203X;GF-109203X; | ||
SMILES | |||
化学名称 | |||
分子式 | C25H24N4O2 | 分子量 | 412.49 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | GF109203X, as an ATP-competitive PKC inhibitor, prevents platelet aggregation induced by stimuli that activate PKC, and has the potential as a tool for studying the involvement of PKC in signal transduction pathways. GF 109203X produces reversal activity on P-glycoprotein and MRP -mediated multidrug resistance. PKC inhibition by GF109203X significantly reduces carbachol-stimulated ERK1/2 activation and the subsequent proliferation of SNU-407 colon cancer cells. |
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