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CAS号 | 1200493-78-2 | 货号 | BCP25878 |
中文名 | Atabecestat | ||
英文名 | Atabecestat | ||
中文别名 | |||
英文别名 | JNJ-54861911; JNJ54861911; JNJ 54861911; RSC-385896; RSC 385896; RSC385896; | ||
SMILES | CC1(C=CSC(=N1)N)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)C#N)F | ||
化学名称 | |||
分子式 | C18H14FN5OS | 分子量 | 367.4 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. Atabecestat (JNJ-54861911) is tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment. |
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