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CAS号 | 876708-03-1 | 货号 | BCP46487 |
中文名 | RO-9187 | ||
英文名 | RO-9187 | ||
中文别名 | |||
英文别名 | RO 9187; RO9187; | ||
SMILES | C1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O | ||
化学名称 | |||
分子式 | C9H12N6O5 | 分子量 | 284.23 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | RO-9187 is a potent inhibitor of HCV virus replication in the replicon system (IC(50) = 171 +/- 12 nM; CC(50) >1 mM). RO-9187 is an excellent substrate for deoxycytidine kinase and is phosphorylated with efficiencies up to 3-fold higher than deoxycytidine. RO-9187 is a new class of antiviral nucleosides with promising preclinical properties as potential medicines for the treatment of HCV infection. |
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