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CAS号 | 81129-83-1 | 货号 | BCP09574 |
中文名 | 西司他丁钠 | ||
英文名 | Cilastatin sodium | ||
中文别名 | |||
英文别名 | Cilastatin; Cilastatine; Cilastatinum; MK 0791; MK 791; M K-791; MK0791; MK791; | ||
SMILES | |||
化学名称 | |||
分子式 | C16H24N2Na2O5S | 分子量 | 402.42 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Cilastatin is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Dehydropeptidase is an enzyme found in the kidney and is responsible for degrading the antibiotic imipenem. Cilastatin can therefore be combined intravenously with imipenem in order to protect it from dehydropeptidase and prolong its antibacterial effect. Cilastatin itself does not have antibiotic activity although it has been proved to be active against a zinc-dependent beta-lactamase that usually confer antibiotic resistance to certain bacteria. |
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