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CAS号 | 495076-64-7 | 货号 | BCP33172 |
中文名 | Org 25543 hydrochloride | ||
英文名 | Org 25543 hydrochloride | ||
中文别名 | |||
英文别名 | ORG25543 HCl; Org 25543 HCl;Org-25543 HCl; | ||
SMILES | CN(C)C1(CCCC1)CNC(=O)C2=CC(=C(C(=C2)OC)OCC3=CC=CC=C3)OC.Cl | ||
化学名称 | |||
分子式 | C24H32lN2O4.HCl | 分子量 | 448.99 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 other common biological targets (≥ 100 μM), in a glycine uptake assay in CHO cells. Ameliorates mechanical allodynia after partial sciatic nerve ligation injury in mice. |
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