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CAS号 | 28395-03-1 | 货号 | BCP28485 |
中文名 | 布美他尼 | ||
英文名 | Bumetanide | ||
中文别名 | |||
英文别名 | Ro 10-6338; PF 1593;Ro-10-6338; PF1593;Ro10-6338; PF-1593; | ||
SMILES | CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2 | ||
化学名称 | |||
分子式 | C17H20N2O5S | 分子量 | 364.42 |
纯度 | 99% | 配送 | 惯例下常温包邮 |
产品描述 | Bumetanide is a loop diuretic of the sulfamyl category to treat heart failure. It is often used in people in whom high doses of furosemide are ineffective. It is marketed by Hoffmann-La Roche. The main difference between the two substances is in bioavailability and pharmacodynamic potency. Furosemide is incompletely absorbed in the intestine (60%), and there are substantial inter- and intraindividual differences in bioavailability (range 10-90%). Bumetanide is almost completely absorbed (80%), and the absorption is not altered when it is taken with food. It is said to be a more predictable diuretic, meaning that the predictable absorption is reflected in a more predictable effect. |
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