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Bumetanide 结构式

布美他尼

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货号 :BCP28485CAS号 :28395-03-1纯度:99%
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  • 基本信息与产品描述
CAS号 28395-03-1 货号 BCP28485
中文名 布美他尼
英文名 Bumetanide
中文别名
英文别名 Ro 10-6338; PF 1593;Ro-10-6338; PF1593;Ro10-6338; PF-1593;
SMILES CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2
化学名称
分子式 C17H20N2O5S 分子量 364.42
纯度 99% 配送 惯例下常温包邮
产品描述 Bumetanide is a loop diuretic of the sulfamyl category to treat heart failure. It is often used in people in whom high doses of furosemide are ineffective. It is marketed by Hoffmann-La Roche. The main difference between the two substances is in bioavailability and pharmacodynamic potency. Furosemide is incompletely absorbed in the intestine (60%), and there are substantial inter- and intraindividual differences in bioavailability (range 10-90%). Bumetanide is almost completely absorbed (80%), and the absorption is not altered when it is taken with food. It is said to be a more predictable diuretic, meaning that the predictable absorption is reflected in a more predictable effect.
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