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CAS号 | 2248666-66-0 | 货号 | BCP39849 |
关联产品 | 947303-87-9(PF429242) | ||
中文名 | PF429242 dihydrochloride | ||
英文名 | PF429242 dihydrochloride | ||
中文别名 | |||
英文别名 | PF429242 dihydrochloride;PF429242 2HCl;PF 429242 2HCl;PF-429242 2HCl; | ||
SMILES | CCN(CC)CC1=CC=C(C=C1)C(=O)N(CCC2=CC=CC=C2OC)C3CCNC3.Cl.Cl | ||
化学名称 | |||
分子式 | C25H37Cl2N3O2 | 分子量 | 482.49 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | PF 429242 is a reversible and competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM), a transcriptional regulators of cholesterol, fatty acid, and glucose metabolism. It reduces hepatic synthesis of cholesterol and fatty acid in mice. |
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