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Bilastine 结构式

比拉斯汀

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货号 :BCP02576CAS号 :202189-78-4纯度:98%
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  • 基本信息与产品描述
CAS号 202189-78-4 货号 BCP02576
中文名 比拉斯汀
英文名 Bilastine
中文别名
英文别名 Bilastinum;Ilaxten;
SMILES
化学名称
分子式 C28H37N3O3 分子量 463.61
纯度 98% 配送 惯例下常温包邮
产品描述 Bilastine binds to histamine H1-receptors as indicated by its displacement of [3H]-pyrilamine from H1-receptors expressed in guinea-pig cerebellum and human embryonic kidney (HEK) cell lines. The studies conducted on guinea-pig smooth muscle demonstrated the capability of bilastine to antagonise H1-receptors. Bilastine is selective for histamine H1-receptors as shown in receptor-binding screening conducted to determine the binding capacity of bilastine to 30 different receptors . Bilastine distribution has an apparent volume of distribution of 1.29 L/kg, and has an elimination half-life of 14.5 h and plasma protein binding of 84-90% .
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