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RO2959 Hydrochloride 结构式

RO2959 Hydrochloride

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货号 :BCP37822CAS号 :1219927-22-6纯度:98%
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  • 基本信息与产品描述
CAS号 1219927-22-6 货号 BCP37822
中文名 RO2959 Hydrochloride
英文名 RO2959 Hydrochloride
中文别名
英文别名 RO2959 HCl;RO 2959 HCl;RO-2959 HCl;RO-2959 Hydrochloride;
SMILES CC1=C(CN(CC1)C2=NC=C(S2)C)C3=CN=C(C=N3)NC(=O)C4=C(C=CC=C4F)F.Cl
化学名称
分子式 C21H20ClF2N5OS 分子量 463.93
纯度 98% 配送 惯例下常温包邮
产品描述 RO2959 hydrochloride is a potent and selective CRAC channel inhibitor with an IC50 of 402 nM. RO2959 hydrochloride is a potent blocker of store operated calcium entry (SOCE) mediated by Orai1/Stim1 channels with an IC50 of 25 nM. RO2959 hydrochloride is also a potent inhibitor of human IL-2 production, and potently blocks T cell receptor triggered gene expression and T cell functional pathways.
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