SRX3207

  • Chemical Properties
CAS No. 2254693-15-5 Cat. No. BCP40266
Name SRX3207
Synonyms SRX 3207;SRX-3207;
Formula C29H29N7O3S M. Wt 555.65
  • Biological Activity
Description SRX3207 is an orally active dual inhibitor of Syk-PI3K with IC50 of 39.9 nM, 31200 nM, 3070 nM, 3070 nM, 244 nM, 388 nM, 9790 nM for Syk, Zap70, BRD41, BRD42, PI3K alpha, PI3K delta, PI3K gamma, respectively. SRX3207 blocks tumor immunosuppression and increases anti-tumor immunity.
Pathways Angiogenesis/Protein Tyrosine Kinase PI3K/Akt/mTOR Epigenetics 
Targets Epigenetic Reader Domain PI3K Syk 

Structure

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