YN968D1 Hydrochloride
CAS号 | 1218779-89-5 | 货号 | BCP16050 |
中文名 | YN968D1 Hydrochloride | ||
英文名 | YN968D1 Hydrochloride | ||
中文别名 | |||
英文别名 | Apatinib Hydrochloride;YN968D-1 Hydrochloride;YN968D 1 Hydrochloride; | ||
分子式 | C24H24ClN5O | 分子量 | 433.93 |
生物活性 | Apatinib, also known as YN968D1, is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activities. The free-base form is also known as Rivoceranib. Apatinib selectively binds to and inhibits vascular endothelial growth factor receptor 2, which may inhibit VEGF-stimulated endothelial cell migration and proliferation and decrease tumor microvessel density. In addition, this agent mildly inhibits c-Kit and c-SRC tyrosine kinases. | ||
信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
靶 点 | VEGFR RET |
结构式
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