Almonertinib mesylate
| CAS No. | 2134096-06-1 | Cat. No. | BCP48089 |
| Name | Almonertinib mesylate | ||
| Synonyms | HS-10296 mesylate;HS10296 mesylate;HS 10296 mesylate; | ||
| Formula | C31H39N7O5S | M. Wt | 621.76 |
| Description | Almonertinibmesylate is an orally available, irreversible, third-generation EGFR tyrosine kinase inhibitor with high selectivity for EGFR-sensitizing and T790M resistance mutations. Almonertinib mesylate shows great inhibitory activity against T790M, T790M/L858R and T790M/Del19 (IC50: 0.37, 0.29 and 0.21 nM, respectively), and is less effective against wild type (3.39 nM). Almonertinib mesylate is used for the research of the non-small cell lung cancer. | ||
| Related Products | 2134096-03-8（Almonertinib hydrochloride） 1899921-05-1（Almonertinib） | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | EGFR | ||
Structure
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