Disitertide

  • Chemical Properties
CAS No. 272105-42-7 Cat. No. BCP46789
Name Disitertide
Synonyms P144;P-144;P 144;
Formula C68H109N17O22S2 M. Wt 1580.84
  • Biological Activity
Description Disitertide prevents TGF-β1-dependent inhibition of MV1Lu proliferation in vitro and markedly reduces binding of TGF-β1 to its receptors. Disitertide blocks TGF-β1-dependent stimulation of a reporter gene under the control of human α2(I) collagen promoter.
Pathways TGF beta/Smad  PI3K/Akt/mTOR 
Targets TGF β/Smad PI3K 

Structure

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