BVT948
| CAS No. | 39674-97-0 | Cat. No. | BCP45529 |
| Name | BVT948 | ||
| Synonyms | BVT-948; BVT 948; SPS8I3; SPS-8I3; SPS 8I3; | ||
| Formula | C14H11NO3 | M. Wt | 241.24 |
| Description | BVT948 is a protein tyrosine phosphatases (PTP) inhibitor (IC50 = 0.09 - 1.7 μM). BVT948 inhibits NF-κB activation by suppressing IκBα degradation and the nuclear translocation of NF-κB in TPA-treated MCF-7 cells. BVT948 didn’t block TPA-induced AP-1 activation in MCF-7 cells. BVT948 blocks MMP-9 expression of breast cancer cells by inhibiting the TPA-stimulated NF-κB pathway. | ||
| Pathways | Protease/Metabolic Enzyme Epigenetics | ||
| Targets | Histone Methyltransferase Cytochrome P450 Phosphatase | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.