Gusacitinib hydrochloride
| CAS No. | 2228989-14-6 | Cat. No. | BCP35707 |
| Name | Gusacitinib hydrochloride | ||
| Synonyms | ASN-002 Hydrochloride;ASN-002 HCl; | ||
| Formula | C24H29ClN8O2 | M. Wt | 497 |
| Description | Gusacitinib (ASN-002) is an orally active and potent dual inhibitor of spleen tyrosine kinase (SYK) and janus kinase (JAK) with IC50 values of 5-46 nM. Gusacitinib has anti-cancer activity in both solid and hematological tumor types. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
| Targets | JAK Syk | ||
Structure
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