Hydroxy-Fasudil
| CAS No. | 105628-72-6 | Cat. No. | BCP29679 |
| Name | Hydroxy-Fasudil | ||
| Synonyms | Hydroxyfasudil; HA-1100; | ||
| Formula | C14H17N3O3S | M. Wt | 307.37 |
| Description | Hydroxy-Fasudil is a metabolite of Fasudil, acting as a potent Rho-kinase inhibitor and vasodilator.Hydroxyfasudil is a ROCK inhibitor, with IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively. | ||
| Pathways | Cell Cycle/DNA Damage TGF beta/Smad Wnt/Stem Cell | ||
| Targets | ROCK | ||
Structure
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