AV-412 Tosylate

  • 化学数据
CAS号 451493-31-5 货号 BCP23783
中文名 AV-412 Tosylate
英文名 AV-412 Tosylate
中文别名
英文别名 MP-412; MP 412; MP412; AV-412; AV 412; AV412;
分子式 C41H44ClFN6O7S2 分子量 851.41
  • 用途
生物活性 AV-412, also known as MP-412, is a second-generation, orally bioavailable dual kinase inhibitor with potential antineoplastic activity. EGFR/HER2 inhibitor AV-412 binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis, and tumor regression in EGFR/HER2-expressing tumors. This agent may be active against EGFR/HER2-expressing tumor cells that are resistant to first-generation kinase inhibitors. EGFR and HER2 are receptor tyrosine kinases that play major roles in tumor cell proliferation and tumor vascularization.
信号通路 Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway 
靶 点 EGFR HER2 

结构式

本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
全国免费电话:400-099-8200
在线客服:
技术支持:
orders@biochempartner.com
瀚香官网:
www.biochempartner.com
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!