BIO-acetoxime
| CAS No. | 667463-85-6 | Cat. No. | BCP27976 |
| Name | BIO-acetoxime | ||
| Synonyms | BIA; GSK-3 Inhibitor X;6-bromoindirubin-3'-acetoxime; | ||
| Formula | C18H12BrN3O3 | M. Wt | 398.22 |
| Description | BIO-Acetoxime is a potent and selective GSK-3a/b inhibitor that reduces invasiveness of gliomas and extends animal survival in intracranial glioma models. Also, BIO-Acetoxime induces Wnt signaling and inhibits CD8+ T cell effector differentiation. BIO-acetoxime is a synthetic derivative of a compound from the Mediterranean mollusk Hexaplex trunculus. BIO-Acetoxime protects cells from varicella infection. BIO-acetoxime may suppress viral gene expression and protect oral epithelial cells from HSV-1 infection. | ||
| Pathways | Wnt/Stem Cell PI3K/Akt/mTOR | ||
| Targets | GSK3 | ||
Structure
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