Bromosporine
| CAS No. | 1619994-69-2 | Cat. No. | BCP08268 |
| Name | Bromosporine | ||
| Synonyms | |||
| Formula | C17H20N6O4S | M. Wt | 404.445 |
| Description | In cell-based assays, Bromosporine (1 μM) accelerates FRAP recovery of BRD4 and CREBBP, while shows no activities against TIF1α, BAZ2A, and SMARCA2 even at 10 μM. Bromosporine shows moderate cytotoxicity in HeLa cells at 18 μM. Bromosporine, as a chemical probe for bromodomain functional assays, will be very useful in elucidating further biological roles of reader domains. | ||
| Pathways | Epigenetics | ||
| Targets | Epigenetic Reader Domain | ||
Structure
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