Quinacrine dihydrochloride

CAS No.	69-05-6	Cat. No.	BCP49707
Name	Quinacrine dihydrochloride
Synonyms	Quinacrine 2HCl;Mepacrine dihydrochloride; SN-390 dihydrochloride;
Formula	C23H32Cl3N3O	M. Wt	472.88

Description	Quinacrine Hydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities. Quinacrine may inhibit the transcription and activity of both basal and inducible nuclear factor-kappaB (NF-kappaB), which may result in the induction of tumor suppressor p53 transcription, the restoration of p53-dependent apoptotic pathways, and tumor cell apoptosis. Continuous NF-kappaB signaling, present in many tumors and in chronic inflammatory processes, promotes the expression of antiapoptotic proteins and cytokines while downregulating the expression of proapoptotic proteins, such as p53.
Pathways	Microbiology/Virology
Targets	Antiparasitics

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.

For product details of different batches, please contact our Customer

Products are for research use only and not for human use. We do not sell to patients.