CA77.1

  • Chemical Properties
CAS No. 2412270-22-3 Cat. No. BCP48919
Name CA77.1
Synonyms
Formula C16H12ClN3O M. Wt 297.74
  • Biological Activity
Description CA77.1 is a potent, brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics. CA77.1 is a derivative of AR7 and can increase the expression of the lysosomal receptor LAMP2A in lysosomes. CA77.1 improves behavior and neuropathology in PS19 mice model and can be used for alzheimer's disease research.
Pathways Others Pathway 
Targets Autophagy 

Structure

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