GDC-0214
| CAS No. | 1831144-46-7 | Cat. No. | BCP47996 |
| Name | GDC-0214 | ||
| Synonyms | iJak381; iJak 381; iJak-381; GDC 0214; GDC0214; | ||
| Formula | C28H28ClF2N9O3 | M. Wt | 612.04 |
| Description | GDC-0214 is a highly potent, selective, and inhalable Janus kinase-1 (JAK-1) inhibitor which shows about 950 times higher concentration in the lungs than in plasma after inhalation in mice. iJak-381 suppresses the signal transducer and activator of transcription 6 activation by IL-13. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
| Targets | JAK | ||
Structure
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