NI-42
CAS号 | 1884640-99-6 | 货号 | BCP43848 |
中文名 | NI-42 | ||
英文名 | NI-42 | ||
中文别名 | |||
英文别名 | NI 42; NI42; | ||
分子式 | C18H15N3O3S | 分子量 | 353.39 |
生物活性 | NI-42 is a potent and selective BRPF1 in inhibitor with BRPF1 IC50 = 7.9 nM; LE: 0.45; LLE: 5.6. NI-42 is suitable for cellular and in vivo studies to explore the fundamental biology of these proteins. The BRPF (bromodomain and PHD finger-containing) family are scaffolding proteins important for the recruitment of histone acetyltransferases of the MYST family to chromatin. Evaluation of the BRPF family as a potential drug target is at an early stage although there is an emerging understanding of a role in acute myeloid leukemia (AML). | ||
信号通路 | Epigenetics | ||
靶 点 | Epigenetic Reader Domain |
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
- 全国免费电话:400-099-8200
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!