FOXY-5
| CAS No. | 881188-51-8 | Cat. No. | BCP43701 |
| Name | FOXY-5 | ||
| Synonyms | Foxy 5; Foxy5; | ||
| Formula | C26H42N6O12S2 | M. Wt | 694.77 |
| Description | FOXY-5 is a wnt signalling pathway modulator potentially forthe treatment of metastatic breast cancer, prostate cancer and colorectal cancer. In vitro analyses revealed that both recombinant Wnt-5a and the Wnt-5a-derived Foxy-5 peptide impaired migration and invasion without affecting apoptosis or proliferation of 4T1 breast cancer cells. The in vivo experiments show that i.p. injections of Foxy-5 inhibited metastasis of inoculated 4T1 breast cancer cells from the mammary fat pad to the lungs and liver by 70% to 90%. | ||
| Pathways | Wnt/Stem Cell | ||
| Targets | Wnt | ||
Structure
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