BRD0705
| CAS No. | 2056261-41-5 | Cat. No. | BCP33275 |
| Name | BRD0705 | ||
| Synonyms | BRD-0705; BRD 0705; | ||
| Formula | C20H23N3O | M. Wt | 321.42 |
| Description | BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC50 of 66 nM and a Kd of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML) research. | ||
| Pathways | Wnt/Stem Cell PI3K/Akt/mTOR | ||
| Targets | GSK3 | ||
Structure
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