Pralsetinib
CAS No. | 2097132-94-8 | Cat. No. | BCP29411 |
Name | Pralsetinib | ||
Synonyms | BLU 667;BLU667;BLU-667; | ||
Formula | C27H32FN9O2 | M. Wt | 533.61 |
Description | Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC50s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | RET |
Structure
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