FGF401
| CAS号 | 1708971-55-4 | 货号 | BCP25143 |
| 中文名 | FGF401 | ||
| 英文名 | FGF401 | ||
| 中文别名 | |||
| 英文别名 | FGF-401; FGF 401; Roblitinib; | ||
| 分子式 | C25H30N8O4 | 分子量 | 506.56 |
| 生物活性 | FGF401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity. Upon administration, FGF401 binds to and inhibits the activity of FGFR4, which leads to an inhibition of tumor cell proliferation in FGFR4-overexpressing cells. FGFR4 is a receptor tyrosine kinase upregulated in certain tumor cells and involved in tumor cell proliferation, differentiation, angiogenesis, and survival. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | FGFR | ||
结构式
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