布拉扑兰
CAS号 | 1562338-42-4 | 货号 | BCP19909 |
中文名 | 布拉扑兰 | ||
英文名 | Branaplam | ||
中文别名 | |||
英文别名 | LMI-070;LMI070;LMI 070;NVS-SM1; | ||
分子式 | C22H27N5O2 | 分子量 | 393.48 |
生物活性 | Branaplam, also known as NVS-SM1 and LMI-070, is a highly potent, selective and orally active small molecule SMN2 splicing modulator as a potential treatment for SMA Type 1 (Spinal Muscular Atrophy) .NVS-SM1 works by increasing the amount of functional SMN protein produced by the “back-up” gene, SMN2, through modifying its splicing. | ||
上下游产品 | 1562338-39-9(Branaplam hydrochloride) | ||
信号通路 | Cell Cycle/DNA Damage | ||
靶 点 | DNA/RNA Synthesis |
结构式
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