Src Kinase Inhibitor I
CAS号 | 179248-59-0 | 货号 | BCP24909 |
中文名 | Src Kinase Inhibitor I | ||
英文名 | Src Kinase Inhibitor I | ||
中文别名 | |||
英文别名 | Src I1; Src I-1; SrcI1; | ||
分子式 | C22H19N3O3 | 分子量 | 373.4 |
生物活性 | Src Inhibitor-1 is a member of the class of quinazolines that is quinazoline which is substituted at position 4 by a p-phenoxyanilino group and at positions 6 and 7 by methoxy groups. It is a potent, competitive dual site (both the ATP- and peptide-binding) Src kinase inhibitor. Src Inhibitor-1 is one of the 'gold standards' for Src kinase inhibition that has been shown to use PP1 or PP2 in parallel with Src-I1 to inhbit Src family kinases. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of quinazolines, a secondary amino compound, an aromatic ether and a polyether. | ||
信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
靶 点 | Src/Bcr Abl |
结构式
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