CEP-28122 monomesilate hydrochloride salt
| CAS号 | 1354545-57-5 | 货号 | BCP24832 |
| 中文名 | CEP-28122 monomesilate hydrochloride salt | ||
| 英文名 | CEP-28122 monomesilate hydrochloride salt | ||
| 中文别名 | |||
| 英文别名 | CEP 28122 monomesilate hydrochloride salt;CEP28122 monomesilate hydrochloride salt; | ||
| 分子式 | C29H40Cl2N6O6S | 分子量 | 671.64 |
| 生物活性 | CEP-28122 is a highly potent and selective orally active ALK inhibitor with a favorable pharmaceutical and pharmacokinetic profile and robust and selective pharmacologic efficacy against ALK-positive human cancer cells and tumor xenograft models in mice. Anaplastic lymphoma kinase (ALK) is constitutively activated in a number of human cancer types due to chromosomal translocations, point mutations, and gene amplification and has emerged as an excellent molecular target for cancer therapy. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | ALK | ||
结构式
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