Vericiguat

  • Chemical Properties
CAS No. 1350653-20-1 Cat. No. BCP18886
Name Vericiguat
Synonyms BAY1021189; BAY 1021189; BAY-1021189; BAY10-21189; BAY-10-21189; BAY 10-21189;
Formula C19H16F2N8O2 M. Wt 426.38
  • Biological Activity
Description Vericiguat, also known as BAY1021189 or BAY10-21189, is a potent and orally active sGC stimulator (Soluble Guanylate Cyclase Stimulator). Direct stimulation of soluble guanylate cyclase (sGC) is emerging as a potential new approach for the treatment of renal disorders. sGC catalyzes the formation of cyclic guanosine monophosphate (cGMP), deficiency of which is implicated in the pathogenesis of chronic kidney disease (CKD).
Pathways GPCR/G Protein 
Targets Guanylate Cyclase 

Structure

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