ORM-12741
| CAS No. | 610782-82-6 | Cat. No. | BCP24175 |
| Name | ORM-12741 | ||
| Synonyms | ORM12741; ORM 12741;ORM 10921;ORM10921;ORM-10921; | ||
| Formula | C18H23NO2 | M. Wt | 285.38 |
| Description | ORM-12741 is an α-2c adrenergic receptor antagonist. In the behavioural tests, ORM-10921 displayed potent antidepressant and antipsychotic-like effects in the forced swimming test and prepulse-inhibition models analogously. In the pharmacodynamic microdialysis study, ORM-10921 was found to increase extracellular dopamine levels in prefrontal cortex in the baseline conditions. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | Adrenergic Receptor | ||
Structure
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