Lenrispodun
| CAS号 | 1160521-50-5 | 货号 | BCP16186 |
| 中文名 | Lenrispodun | ||
| 英文名 | Lenrispodun | ||
| 中文别名 | |||
| 英文别名 | ITI-214; ITI 214; ITI214; PDE1-IN-1;PDE4 (R)-(-)-Rolipram; | ||
| 分子式 | C29H26FN7O | 分子量 | 507.56 |
| 生物活性 | ITI-214 is an orally active, potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases. ITI-214 exhibited picomolar inhibitory potency for PDE1, demonstrated excellent selectivity against all other PDE families, and showed good efficacy in vivo. Currently, this investigational new drug is in Phase I clinical development and being considered for the treatment of several indications including cognitive deficits associated with schizophrenia and Alzheimer's disease, movement disorders, attention deficit and hyperactivity disorders, and other CNS and non-CNS disorders. | ||
| 上下游产品 | 1642303-38-5（Lenrispodun phosphate） | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | Phosphodiesterase/PDE | ||
结构式
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