BI 847325
| CAS No. | 1207293-36-4 | Cat. No. | BCP15994 |
| Name | BI 847325 | ||
| Synonyms | BI-847325;BI847325; | ||
| Formula | C29H28N4O2 | M. Wt | 464.56 |
| Description | BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. | ||
| Pathways | Cell Cycle/DNA Damage MAPK Pathway Epigenetics | ||
| Targets | MEK/ERK Aurora | ||
Structure
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