Colistimethate Sodium

  • Chemical Properties
CAS No. 8068-37-9 Cat. No. BCP15947
Name Colistimethate Sodium
Synonyms Colistimethate;Colistin sodium methanesulfonate;
Formula C58H105N16Na5O28S5 M. Wt 1749.81
  • Biological Activity
Description Colistimethate is a broad-spectrum polymyxin antibiotic against most aerobic Gram-negative bacteria except Proteus bacteria. Colistimethate is a mixture of methanesulfonate derivatives of cyclic polypeptides colistin A and B from Bacillus colistinus or B. polymyxa. Colistin functions as a surfactant which penetrates into and disrupts the bacterial cell membrane, thereby resulting in bactericidal effect.
Pathways Microbiology/Virology 
Targets Antibiotic 

Structure

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