BD-1047二氢溴酸盐

  • 化学数据
CAS号 138356-21-5 货号 BCP15756
中文名 BD-1047二氢溴酸盐
英文名 BD1047 dihydrobromide
中文别名
英文别名 BD-1047 dihydrobromide;BD 1047 dihydrobromide; BD-1047 2HBr;
分子式 C13H20Cl2N2.2HBr 分子量 437.04
  • 用途
生物活性 BD-1047 dihydrobromide is a selective functional antagonist of sigma receptors, shows antipsychotic activity in animal models predictive of efficacy in schizophrenia.BD1047 is a potent and selective Sigma-1 Receptor Antagonist. It has effects in animal studies suggestive of antipsychotic activity and may also be useful in the treatment of neuropathic pain. BD-1047 has >50-fold selectivity at σ1 over σ2 and also >100-fold selectivity over opiate, phencyclidine, muscarinic, dopamine, α1- & α2-adrenoceptor, 5-HT1, and 5-HT2.
信号通路 GPCR/G Protein 
靶 点 Sigma Receptor 

结构式

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