WIKI4

  • 化学数据
CAS号 838818-26-1 货号 BCP15357
中文名 WIKI4
英文名 WIKI4
中文别名
英文别名 WIKI 4; WIKI-4;
分子式 C29H23N5O3S 分子量 521.59
  • 用途
生物活性 WIKI4 is a novel inhibitor of tankyrase and Wnt/ß-catenin signaling. WIKI4 inhibits expression of ß-catenin target genes and cellular responses to Wnt/ß-catenin signaling in cancer cell lines as well as in human embryonic stem cells. WIKI4 mediates its effects on Wnt/ß-catenin signaling by inhibiting the enzymatic activity of TNKS2, a regulator of AXIN ubiquitylation and degradation. While TNKS has previously been shown to be the target of small molecule inhibitors of Wnt/ß-catenin signaling, WIKI4 is structurally distinct from previously identified TNKS inhibitors.
信号通路 Wnt/Stem Cell 
靶 点 Beta catenin 

结构式

本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
全国免费电话:400-099-8200
在线客服:
技术支持:
orders@biochempartner.com
瀚香官网:
www.biochempartner.com
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!