ILK-IN-1
CAS号 | 1333146-24-9 | 货号 | BCP23690 |
中文名 | ILK-IN-1 | ||
英文名 | ILK-IN-1 | ||
中文别名 | |||
英文别名 | ILK-IN-2;OSU-T315 analog;OSU-T315 (1,5-regioisomer);ILK inhibitor 22(1,5); | ||
分子式 | C30H30F3N5O | 分子量 | 533.59 |
生物活性 | OSU-T315 (1,5-regioisomer) is a potent and specific integrin-linked kinase (ILK) inhibitor which inhibits PDK2 function in the AKT pathway activation, showing a specific mechanism of abrogating the AKT pathway and inhibition of BCR activity in the leukemic cell. OSU-T315 also acts as a selective inhibitor of biofilm formation. | ||
信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
靶 点 | Integrin |
结构式
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