番泻苷 B
CAS号 | 128-57-4 | 货号 | BCP14631 |
中文名 | 番泻苷 B | ||
英文名 | Sennoside B | ||
中文别名 | |||
英文别名 | |||
分子式 | C42H38O20 | 分子量 | 862.74 |
生物活性 | Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation. These compounds are present in several drugs of plant origin, especially as O- or C-glycosides. Besides featuring different substituents, the aglycone might consist of an anthraquinone, an anthrone or a dianthrone. So far, detailed information concerning their metabolism and pharmacokinetic characteristics is available only in a few cases. The best characterized compounds are sennoside, a dianthrone O-glycoside present in senna leaves and senna pods, and its aglycone (rhein anthrone). After oral administration, sennoside is degraded only in the lower parts of the gastrointestinal tract, releasing its active metabolite rhein anthrone. | ||
信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
靶 点 | PDGFR |
结构式
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