O-去甲文拉法辛

  • 化学数据
CAS号 93413-62-8 货号 BCP28517
中文名 O-去甲文拉法辛
英文名 O-Desmethylvenlafaxine
中文别名
英文别名 Desvenlafaxine;
分子式 C16H25NO2 分子量 263.38
  • 用途
生物活性 Desvenlafaxine (brand name: Pristiq, Desfax), also known as O-desmethylvenlafaxine, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class developed and marketed by Wyeth (now part of Pfizer). Desvenlafaxine is a synthetic form of the major active metabolite of venlafaxine (sold under the brand names Effexor and Efexor). It is being targeted as the first non-hormonal based treatment for menopause. Desvenlafaxine is a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state.
信号通路 Neuro Signaling Pathway 
靶 点 SSRI 

结构式

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