依那西普
| CAS号 | 185243-69-0 | 货号 | BCP12862 |
| 中文名 | 依那西普 | ||
| 英文名 | Etanercept | ||
| 中文别名 | |||
| 英文别名 | TNFR-Fc fusion protein; | ||
| 分子式 | C2224H3475N621O698S36 | 分子量 | 51234.9 |
| 生物活性 | Etanercept is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. The biosimilar is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids and has an apparent molecular weight of approximately 150 kDa. | ||
| 信号通路 | Apoptosis Pathway | ||
| 靶 点 | TNF Receptor | ||
结构式
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