(S)-酮咯酸

  • 化学数据
CAS号 66635-92-5 货号 BCP28452
中文名 (S)-酮咯酸
英文名 (S)-Ketorolac
中文别名 酮咯酸S-异构体;
英文别名 Ketorolac S-Isomer;(-)-Ketorolac;
分子式 C15H13NO3 分子量 255.26
  • 用途
生物活性 (S)-ketorolac is a 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known simply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. It has a role as an analgesic, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor and a non-steroidal anti-inflammatory drug. It is an enantiomer of a (R)-ketorolac.
信号通路 Neuro Signaling Pathway 
靶 点 COX 

结构式

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