SMCC
CAS No. | 64987-85-5 | Cat. No. | BCP10445 |
Name | SMCC | ||
Synonyms | SMCC, heterobifunctional cross-linker; SMCC crosslinker; | ||
Formula | C16H18N2O6 | M. Wt | 334.32 |
Description | SMCC is a heterobifunctional protein crosslinker. SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane-stabilized spacer arm (8.3 angstroms). SMCC conjugation occurs via a maleimide group that is sulfhydryl (thiol; -SH) reactive and a NHS ester group that is amine reactive and forms stable, covalent protein crosslinks. | ||
Pathways | Others Pathway | ||
Targets | ADC Related |
Structure
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