SMCC

  • Chemical Properties
CAS No. 64987-85-5 Cat. No. BCP10445
Name SMCC
Synonyms SMCC, heterobifunctional cross-linker; SMCC crosslinker;
Formula C16H18N2O6 M. Wt 334.32
  • Biological Activity
Description SMCC is a heterobifunctional protein crosslinker. SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane-stabilized spacer arm (8.3 angstroms). SMCC conjugation occurs via a maleimide group that is sulfhydryl (thiol; -SH) reactive and a NHS ester group that is amine reactive and forms stable, covalent protein crosslinks.
Pathways Others Pathway 
Targets ADC Related 

Structure

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