诃子林鞣酸
CAS号 | 18942-26-2 | 货号 | BCP09990 |
中文名 | 诃子林鞣酸 | ||
英文名 | Chebulinic acid | ||
中文别名 | 柯黎勒酸; | ||
英文别名 | NSC69862;NSC-69862;NSC 69862;Eutannin; | ||
分子式 | C41H32O27 | 分子量 | 956.68 |
生物活性 | Chebulinic Acid is a potent protectant against glutamate-induced neuronal cell death. It has been shown to significantly reduce intracellular reactive oxygen species (ROS) production and Ca2+ influx induced by glutamate, decrease the phosphorylation of mitogen-activated protein kinases (MAPKs), including ERK1/2, JNK, and p38, as well as inhibit pro-apoptotic Bax and increase anti-apoptotic Bcl-2 protein expression. | ||
信号通路 | Ion Channel/Membrane Transporter Cell Cycle/DNA Damage TGF beta/Smad Wnt/Stem Cell | ||
靶 点 | DNA/RNA Synthesis TGF β/Smad Proton Pump |
结构式
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